Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myeloid cell plasticity in the evolution of central nervous system autoimmunity.

Annals of neurology - 1 Jan 2018

Giles David A, Washnock-Schmid Jesse M, Duncker Patrick C, Dahlawi Somiah, Ponath Gerald, Pitt David, Segal Benjamin M

Abstract excerpt

OBJECTIVE: Myeloid cells, including macrophages and dendritic cells, are a prominent component of central nervous system (CNS) infiltrates during multiple sclerosis (MS) and the animal model experimental autoimmune encephalomyelitis (EAE). Although myeloid cells are generally thought to be proinflammatory, alternatively polarized subsets can serve noninflammatory and/or reparative functions. Here we investigate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arginase
Share to Autoimmune Diseases of the Nervous System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Plasticity

Share to Encephalomyelitis, Autoimmune, Experimental

Share to Mannose-Binding Lectins

Share to Mannose Receptor

Share to Myeloid Cells

Share to Nitric Oxide Synthase Type II

Source

Open in PubMed Open full text

Identifiers

PMID: 29283442
DOI: 10.1002/ana.25128
PMCID: PMC5876132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myeloid cell plasticity in the evolution of central nervous system autoimmunity.PMID 29283442Read ↗

The Role of Distinct Subsets of Macrophages in the Pathogenesis of MS and the Impact of Different Therapeutic Agents on These Populations.Semantic proximity Read ↗

Specific myeloid signatures in peripheral blood differentiate active and rare clinical phenotypes of multiple sclerosis.Semantic proximity Read ↗

Alternatively activated neutrophils limit T cell–driven neuroinflammationSemantic proximity Read ↗

Harnessing monocyte-derived macrophages to control central nervous system pathologies: no longer 'if' but 'how'.Semantic proximity Read ↗

Mapping Leukocyte Dynamics during Neuroinflammation Identifies Meningeal Monocyte-Derived Macrophages as Drivers of Progressive DiseaseSemantic proximity Read ↗

Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function.Semantic proximity Read ↗

CD11c <sup>+</sup> CD88 <sup>+</sup> CD317 <sup>+</sup> myeloid cells are critical mediators of persistent CNS autoimmunitySemantic proximity Read ↗

The immunology of multiple sclerosis.Semantic proximity Read ↗

Molecular signature of slowly expanding lesions in progressive multiple sclerosisSemantic proximity Read ↗

Role of Immune Cells in Multiple Sclerosis and Experimental Autoimmune EncephalomyelitisSemantic proximity Read ↗

Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration.Semantic proximity Read ↗

Immune Regulatory Functions of Macrophages and Microglia in Central Nervous System DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.