Article

Quantifying Treatment Resistance in Mixtures of Gastrointestinal Stromal Tumor Cells with BARMIX

2026-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Targeted therapies in gastrointestinal stromal tumors (GIST) often fail due to heterogeneous resistance mutations arising across metastatic sites. Efficient, rational design of mutation-specific therapies requires the ability to quantify treatment resistance across many genotypes in parallel. Here, we present BARcode MIXture analysis (BARMIX), a platform combining multiplexed experiments with DN...

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Literature Corpus work: 1db7ae4e-f39b-567c-9acb-5284cfd32b4b
DOI: 10.64898/2026.03.23.713602

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