Article
Genomic screening methodology not requiring barcoding: Single nucleotide polymorphism-based, mixed-cell screening (SMICS).
Genomics - 1 Sept 2023
Zhang Zhuwei, Chen Xi, Zhang Wen, Liu Jinpeng, Xie Yanqi, Zhang Shulin, Stromberg Arnold J, Watt David S, Liu Xifu, Wang Chi, Liu Chunming
Abstract excerpt
Although high-throughput, cancer cell-line screening is a time-honored, important tool for anti-cancer drug development, this process involves the testing of each, individual drug in each, individual cell-line. Despite the availability of robotic liquid handling systems, this process remains a time-consuming and costly investment. The Broad Institute developed a new method called Profiling Relative Inhibition...
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