Article

A Novel Type 2 Diabetes Locus in sub-Saharan Africans, <i>ZRANB3</i> , is Implicated in Beta Cell Proliferation

2019-05-24

Abstract excerpt

Genome analysis of diverse human populations has contributed to the identification of novel genomic loci for diseases of major clinical and public health impact. Here, we report the largest genome-wide analysis of type 2 diabetes (T2D) in sub-Saharan Africans, an understudied ancestral group. We analyzed ~18 million autosomal SNPs in 5,231 individuals from Nigeria, Ghana and Kenya. TCF7L2 rs7903156 was the most s...

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Literature Corpus work: 1d96e857-3cfb-55d7-889b-8a073172e7a9
DOI: 10.1101/646513

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