Article
Evaluation of genome-wide association study-identified type 2 diabetes loci in African Americans.
American journal of epidemiology - 1 Dec 2012
Long Jirong, Edwards Todd, Signorello Lisa B, Cai Qiuyin, Zheng Wei, Shu Xiao-Ou, Blot William J
Abstract excerpt
Type 2 diabetes (T2D) is up to twice as prevalent among African Americans as Caucasians. Recent genome-wide association studies (GWAS) have identified multiple common genetic risk variants for T2D; however, none of these studies were conducted exclusively among subjects of African ancestry. Investigating these known loci in other populations would be an expedient way to evaluate the generalizability of the...
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