Article
A genome-wide search for type 2 diabetes susceptibility genes in an extended Arab family.
Annals of human genetics - 1 Nov 2013
Al Safar Habiba S, Cordell Heather J, Jafer Osman, Anderson Denise, Jamieson Sarra E, Fakiola Michaela, Khazanehdari Kamal, Tay Guan K, Blackwell Jenefer M
Abstract excerpt
Twenty percent of people aged 20 to 79 have type 2 diabetes (T2D) in the United Arab Emirates (UAE). Genome-wide association studies (GWAS) to identify genes for T2D have not been reported for Arab countries. We performed a discovery GWAS in an extended UAE family (N=178; 66 diabetic; 112 healthy) genotyped on the Illumina Human 660 Quad Beadchip, with independent replication of top hits in 116 cases and 199...
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