Article

Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a mouse model of Friedreich’s ataxia

2023-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Friedreich’s ataxia (FA) is a genetic neurodegenerative disease caused by mutation in FXN gene encoding for the mitochondrial protein frataxin (FXN). Patients with FA display an increased risk of developing diabetes that may aggravate disease prognosis. Recent studies have indicated that in addition to increased visceral adiposity, FA patients undergo a low-grade inflammatory state. The expansi...

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Literature Corpus work: 1d3da929-45e9-5504-a454-2a320f5ed4e3
DOI: 10.1101/2023.04.06.535845

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