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A Multi-component Bioinformatics Study on the Construction of a Prognostic Signature of Genes Associated with Diverse Programmed Cell Death in Acute Leukemia and a Multi-perspective Mechanism Exploration

2023-06-22

Abstract excerpt

<h4>Objective: </h4> To evaluate the predictive value of diverse PCD related genes on the prognosis of AML patients and explore their roles in the development of AML and immunomodulatory therapy using bioinformatics methods. Methods We downloaded clinical and transcriptome sequencing data of AML patients from TCGA, GEO, and GTEX databases. Then, we obtained 12 PCD patterns related genes, including apoptosis, necr...

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Literature Corpus work
38759790-f223-5cb6-b3c3-73bbda1b212a
DOI
10.21203/rs.3.rs-2993629/v1
Open publication

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A Multi-component Bioinformatics Study on the Construction of a Prognostic Signature of Genes Associated with Diverse Programmed Cell Death in Acute Leukemia and a Multi-perspective Mechanism ExplorationDOI 10.21203/rs.3.rs-2993629/v1
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