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A Gene Signature Comprising Seven Pyroptosis-Related Genes Predicts Prognosis in Pediatric Patients with Acute Myeloid Leukemia.

Acta haematologica - 1 Jan 2022

He Xin, Jiang Yongfang, Yu Xingbao, He Fei, Gao Haiyan

Abstract excerpt

INTRODUCTION: The aim of the study was to construct a pyroptosis-related risk score (RS) model for the prognosis of acute myeloid leukemia (AML). METHODS: The TARGET (training) and E-MTAB-1216 (validation) datasets were downloaded. Pyroptosis-related genes with differences in expression were identified between the recurrent and nonrecurrent samples of the training dataset. An RS prognostic model comprising seven...

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PMID: 35933981
DOI: 10.1159/000526346

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