Article

MrHAMER2: high-accuracy long-read RNA sequencing to decode isoform-specific variation in viral transcripts during latency

2024-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Alternative splicing (AS) greatly expands the repertoire of proteins encoded by the human genome. Viruses have been shown to hijack AS cellular pathways to sustain replication or lead to latency. In HIV-1 infection, the virus integrates into the host genome, becoming a transcriptional unit that directly engages in AS to regulate its gene expression. Sequencing advances have enabled insights into...

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Literature Corpus work: 65b3cbbf-81fc-5123-a7b8-dc570c3dfe56
DOI: 10.1101/2024.12.19.629526

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