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Obesity-related brain atrophy is independent of Alzheimer’s disease protein pathways

2024-12-16

Abstract excerpt

<h4>Background</h4> Obesity increases the risk for Alzheimer’s disease (AD) and other dementias. Obesity causes structural brain injury, and it has been suggested that this may contribute to the development of AD pathology. Neurodegeneration in AD results from the aggregation of misfolded and dysfunctional tau and amyloid-β. However, it remains unknown whether adiposity-related brain injury acts through tau and am...

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Literature Corpus work
1cf6014b-0d39-5825-add7-37244fad98ac
DOI
10.1101/2024.12.16.24319065
Open publication

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Obesity-related brain atrophy is independent of Alzheimer’s disease protein pathwaysDOI 10.1101/2024.12.16.24319065
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