Article

Adipokines contribute to central-obesity related reductions in myelin-sensitive MRI indices in the fornix

2018-10-11

Abstract excerpt

Midlife obesity is a risk factor of late onset Alzheimer’s disease (LOAD) but why this is the case remains unknown. As systemic inflammation is involved in both conditions, one possibility is that obesity-related neuroinflammation may contribute to the development of LOAD. Neuroinflammation is closely linked to white matter myelin loss, and this can be measured in vivo with quantitative magnetization transfer (qM...

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Literature Corpus work: c065ac89-fc7c-5f1d-aa61-9e8fa6ef4d12
DOI: 10.1101/440990

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