Article

Exploiting variability of single cells to uncover the in vivo hierarchy of miRNA targets

2015-12-23

Abstract excerpt

MiRNAs are post-transcriptional repressors of gene expression that may additionally reduce the cell-to-cell variability in protein expression, induce correlations between target expression levels and provide a layer through which targets can influence each other's expression as 'competing RNAs' (ceRNAs). Here we combined single cell sequencing of human embryonic kidney cells in which the expression of two distinct...

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Literature Corpus work: 1ceb369f-5872-5d38-8f54-af306aa7b7cc
DOI: 10.1101/035097

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