Article

miRSCAPE - Inferring miRNA expression in single-cell clusters

2021-07-30

Abstract excerpt

Micro-RNAs (miRNA) are critical in development, homeostasis, and diseases, including cancer. However, our understanding of miRNA function at cellular resolution is thwarted by the inability of the standard single cell RNA-seq protocols to capture miRNAs. Here we introduce a machine learning tool -- miRSCAPE -- to infer miRNA expression in a sample from its RNA-seq profile. We establish miRSCAPE’s accuracy separate...

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Literature Corpus work: 115db78b-7730-51dc-bacc-2073ab79ef30
DOI: 10.1101/2021.07.29.454389

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