Article

Genome-wide association analysis of 350,000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema

2017-09-29

Abstract excerpt

Even though heritability estimates suggest that the risk of asthma, hay fever and eczema is largely due to genetic factors, previous studies have not explained a large part of the genetics behind these diseases. In this GWA study, we include 346,545 Caucasians from the UK Biobank to identify novel loci for asthma, hay fever and eczema. We further investigate if associated lead SNPs have a significantly larger effe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1cd490d7-8f12-5760-a25c-87b3c6006ce9
DOI: 10.1101/195933

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association analysis of 350,000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczemaDOI 10.1101/195933Read

Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczemaSemantic proximity Read

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.Semantic proximity Read

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.Semantic proximity Read

Identifying Shared Risk Genes for Asthma, Hay Fever, and Eczema by Multi-Trait and Multiomic Association AnalysesSemantic proximity Read

Eleven loci with new reproducible genetic associations with allergic disease risk.Semantic proximity Read

Lessons from ten years of genome‐wide association studies of asthmaSemantic proximity Read

Large-scale Genetic Analysis Identifies 66 Novel Loci for AsthmaSemantic proximity Read

Improving the power to detect risk variants for allergic disease by defining case-control status based on both asthma and hay fever.Semantic proximity Read

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.Semantic proximity Read

Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.Semantic proximity Read

Gene-based association study of rare variants in children of diverse ancestries implicates TNFRSF21 in the development of allergic asthma.Semantic proximity Read

Exon variants associated with asthma and allergy<sup>1</sup>Semantic proximity Read