Article

Large-scale Genetic Analysis Identifies 66 Novel Loci for Asthma

2019-08-29

Abstract excerpt

We carried out a genome-wide association study (GWAS) for asthma in UK Biobank, followed by a meta-analysis with results from the Trans-National Asthma Genetic Consortium (TAGC). 66 novel genomic regions were identified, bringing the number of known asthma susceptibility loci to 211. Significant gene-sex interactions were also observed where susceptibility alleles, either individually or as a function of polygenic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 94809dcc-db15-558e-8a95-bb64e8490c76
DOI: 10.1101/749598

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Large-scale Genetic Analysis Identifies 66 Novel Loci for AsthmaDOI 10.1101/749598Read

Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma.Semantic proximity Read

Lessons from ten years of genome‐wide association studies of asthmaSemantic proximity Read

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.Semantic proximity Read

The genetics of asthma and allergic disorders.Semantic proximity Read

Shared Genetic Architecture between Asthma and Allergic Diseases: A Genome-Wide Cross Trait Analysis of 112,000 Individuals from UK BiobankSemantic proximity Read

Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczemaSemantic proximity Read

Genome-wide association analysis of 350,000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczemaSemantic proximity Read

Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank.Semantic proximity Read

Genetic and genomic approaches to asthma: new insights for the origins.Semantic proximity Read

Asthma genetics 2006: the long and winding road to gene discovery.Semantic proximity Read

Lessons Learned From GWAS of AsthmaSemantic proximity Read

Novel asthma-associated genes from genome-wide association studies: what is their significance?Semantic proximity Read