Article

The Minor Matrix Protein VP24 from Ebola Virus Lacks Direct Lipid-Binding Properties

2020-07-17

Abstract excerpt

Viral protein 24 (VP24) from Ebola virus (EBOV) was first recognized as a minor matrix protein that associates with cellular membranes. However, more recent studies shed light on its roles in inhibiting viral genome transcription and replication, facilitating nucleocapsid assembly and transport, and interfering with immune responses in host cells through downregulation of interferon (IFN)-activated genes. Thus, wh...

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Literature Corpus work: 1cb44c58-560b-5409-8534-d7436f17c946
DOI: 10.20944/preprints202007.0363.v1

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