Article

The SCWISh network is essential for survival under mechanical pressure

2017-06-16

Abstract excerpt

Cells that proliferate within a confined environment build up mechanical compressive stress. For example, mechanical pressure emerges in the naturally space-limited tumor environment. However, little is known about how cells sense and respond to mechanical compression. We developed microfluidic bioreactors to enable the investigation of the effects of compressive stress on the growth of the genetically tractable m...

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Literature Corpus work: 1ca89288-9194-548a-b2a4-d295efcf230c
DOI: 10.1101/150789

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