Article

Prediction-Guided Design of a More Developable FGF21 Construct

2026-07-14

Abstract excerpt

For structural-biology and protein-production pipelines, the hardest part of a difficult protein is not the biology — it is obtaining a well-behaved sample for functional studies. Programs routinely stall at construct design, expression, and purification : deciding where to truncate, which tags to use, how to express, and how to purify so the protein survives concentration and handling. These decisions are still...

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Literature Corpus work: 1c465383-7355-56b1-86f0-0e27030d69e6
DOI: 10.64898/2026.07.13.738140

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