Article

A Structural Domain in the genomic RNA of SARS-CoV-2 Folds into a Compact Granular Structure without the N protein: A Single-Molecule Fluorescence Spectroscopic Investigation

2026-05-15

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) packages its single-stranded genomic RNA (gRNA) having about 30,000 nucleotides into virions by forming 35–40 granular ribonucleoprotein (RNP) units. Each RNP unit has a diameter of ∼15 nm. While it is generally assumed that the assembly of these RNPs is driven by the binding of the nucleocapsid (N) protein to the gRNA in the cytoplasm, the precise molec...

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Literature Corpus work: 1c3f3896-de27-5dd3-812e-61cf90c6d7eb
DOI: 10.64898/2026.05.15.725307

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A Structural Domain in the genomic RNA of SARS-CoV-2 Folds into a Compact Granular Structure without the N protein: A Single-Molecule Fluorescence Spectroscopic InvestigationDOI 10.64898/2026.05.15.725307Read

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