Article
An mRNA Display Approach for Covalent Targeting of a <i>Staphylococcus aureus</i> Virulence Factor
2024-11-08
Abstract excerpt
<h4>ABSTRACT</h4> Staphylococcus aureus ( S. aureus ) is an opportunistic human pathogen that causes over one million deaths around the world each year. We recently identified a family of serine hydrolases termed fluorophosphonate binding hydrolases (Fphs) that play important roles in lipid metabolism and colonization of a host. Because many of these enzymes are only expressed in Staphylococcus bacteria, they a...
Topics
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- Antimicrobial Peptides and Activities
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Bacteriophages and microbial interactions
- Biochemical and Structural Characterization
- Click Chemistry and Applications
- Peptidase Inhibition and Analysis
- RNA and protein synthesis mechanisms
Identifiers and source
- Literature Corpus work
- 1c3af1a1-7678-5e4f-af38-c687ffe7b96b
- DOI
- 10.1101/2024.11.06.622387
