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Chemoproteomics of an Indole-Based Quinone Epoxide Identifies Druggable Vulnerabilities in Vancomycin-Resistant Staphylococcus aureus

26 Jun 2019

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide The alarming global rise in fatalities from multidrug-resistant Staphylococcus aureus ( S. aureus ) infections has underscored a need to develop new therapies to address this epidemic. Chemoproteomics is valuable in identifying targets for new drugs in different human diseases including bacterial infections. Targeting functional cysteines is particularly...

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PMID: 31241934
DOI: 10.1021/acs.jmedchem.9b00774

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