Article

High-dimension to high-dimension screening for detecting genome-wide epigenetic regulators of gene expression

2022-02-22

Abstract excerpt

<h4>Motivation</h4> The advancement of high-throughput technology characterizes a wide range of epigenetic modifications across the genome involved in disease pathogenesis via regulating gene expression. The high-dimensionality of both epigenetic and gene expression data make it challenging to identify the important epigenetic regulators of genes. Conducting univariate test for each epigenetic-gene pair is subjec...

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Literature Corpus work: 1c311485-4eb6-5950-a58f-13028b72cd8f
DOI: 10.1101/2022.02.21.481160

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