Article

Overlapping Group Screening for Detection of Gene-environment Interactions with Application to TCGA High-dimensional Survival Genomic Data

2022-01-27

Abstract excerpt

<h4>Background: </h4> In the context of biomedical and epidemiological research, gene-environment (G-E) interaction is of great significance to the etiology and progression of many complex diseases. In high-dimensional genetic data, two general models, marginal and joint models, are proposed to identify important interaction factors. Most existing approaches for identifying G-E interactions are limited owing to th...

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Literature Corpus work: fba138fe-af50-5b4e-91cd-04947592c633
DOI: 10.21203/rs.3.rs-1283374/v1

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