Article

Percolate: an exponential family JIVE model to design DNA-based predictors of drug response

2022-09-13

Abstract excerpt

<h4>Motivation</h4> Anti-cancer drugs may elicit resistance or sensitivity through mechanisms which involve several genomic layers. Nevertheless, we have demonstrated that gene expression contains most of the predictive capacity compared to the remaining omic data types. Unfortunately, this comes at a price: gene expression biomarkers are often hard to interpret and show poor robustness. <h4>Results</h4> To capt...

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Literature Corpus work: 55dee760-a8de-5346-a532-6bf3938ed063
DOI: 10.1101/2022.09.11.507473

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