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Article

Revealing the architecture of genetic and epigenetic regulation: a maximum likelihood model.

Briefings in bioinformatics - 1 Nov 2014

Wang Fang, Zhang Shaojun, Wen Yanhua, Wei Yanjun, Yan Haidan, Liu Hongbo, Su Jianzhong, Zhang Yan, Che Jianhua

Abstract excerpt

Gene expression is modulated by multiple mechanisms, including genetic and/or epigenetic regulation, and associated with the processes of cellular differentiation and morphogenesis. Single nucleotide polymorphisms (SNPs) and DNA methylation play important roles in regulating gene expression. In this study, we focused on revealing the relationship between SNPs, DNA methylation and gene expression in two human...

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PMID: 24174551
DOI: 10.1093/bib/bbt076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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