Article

Polygenic risk score based on weight gain trajectories is predictive of childhood obesity

2019-04-11

Abstract excerpt

Obesity is highly heritable, yet only a small fraction of its heritability has been attributed to specific genetic variants. These variants are traditionally ascertained from genome-wide association studies (GWAS), which utilize samples with tens or hundreds of thousands of individuals for whom a single summary measurement (e.g., BMI) is collected. An alternative approach is to focus on a smaller, more deeply char...

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Literature Corpus work: 1be28f34-2cb3-594c-9819-26a7c9d34ae4
DOI: 10.1101/606277

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