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Article

Polygenic Risk, Appetite Traits, and Weight Gain in Middle Childhood: A Longitudinal Study.

JAMA pediatrics - 1 Feb 2016

Steinsbekk Silje, Belsky Daniel, Guzey Ismail Cuneyt, Wardle Jane, Wichstrøm Lars

Abstract excerpt

IMPORTANCE: Genome-wide association studies have identified genetic risks for obesity. These genetic risks influence development of obesity partly by accelerating weight gain in childhood. Research is needed to identify mechanisms to inform intervention. Cross-sectional studies suggest appetite traits as a candidate mechanism. Longitudinal studies are needed to test whether appetite traits mediate genetic...

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Identifiers

PMID: 26830872
DOI: 10.1001/jamapediatrics.2015.4472
PMCID: PMC5914161

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