Article
Trans-ancestry genome-wide association study of childhood body mass index identifies novel loci and age-specific effects.
HGG advances - 10 Apr 2025
Downie Carolina G, Shrestha Poojan, Okello Samson, Yaser Mohammad, Lee Harold H, Wang Yujie, Krishnan Mohanraj, Chen Hung-Hsin, Justice Anne E, Chittoor Geetha, Josyula Navya Shilpa, Gahagan Sheila, Blanco Estela, Burrows Raquel, Correa-Burrows Paulina, Albala Cecilia, Santos José L, Angel Bárbara, Lozoff Betsy, Hartwig Fernando Pires, Horta Bernardo, Brina Karisa Roxo, Isasi Carmen R, Qi Qibin, Gallo Linda C, Perreira Krista M, Thyagarajan Bharat, Daviglus Martha, Van Horn Linda, Gonzalez Franklyn, Bradfield Jonathan P, Hakonarson Hakon, Grant Struan F A, Below Jennifer E, Felix Janine, Graff Mariaelisa, Divaris Kimon, North Kari E
Abstract excerpt
Over the past 30 years, obesity prevalence has markedly increased globally, including among children. Although genome-wide association studies (GWASs) have identified over 1,000 genetic loci associated with obesity-related traits in adults, the genetic architecture of childhood obesity is less well characterized. Moreover, most childhood obesity GWASs have been restricted to severely obese children, in relatively...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.