Article

The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

2022-10-28

Abstract excerpt

Norepinephrine (NE) neurons in the locus coeruleus (LC) make long-range projections throughout the central nervous system, playing critical roles in arousal and mood, as well as various components of cognition including attention, learning, and memory. The LC-NE system is also implicated in multiple neurological and neuropsychiatric disorders. Importantly, LC-NE neurons are highly sensitive to degeneration in both...

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Literature Corpus work: 0e4c860c-9203-5024-a134-c79315a28b5a
DOI: 10.1101/2022.10.28.514241

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