Article

Sympathetic NPY controls glucose homeostasis, cold tolerance, and cardiovascular functions in mice

2023-07-26

Abstract excerpt

<h4>Summary</h4> Neuropeptide Y (NPY) is best known for its effects in the brain as an orexigenic and anxiolytic agent and in reducing energy expenditure. NPY is also co-expressed with Norepinephrine (NE) in sympathetic neurons. Although NPY is generally considered to modulate noradrenergic responses, its specific roles in autonomic physiology remain under-appreciated. Here, we show that sympathetic-derived NPY i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 25992049-62f9-5750-971e-185a0e573f2a
DOI: 10.1101/2023.07.24.550381

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sympathetic NPY controls glucose homeostasis, cold tolerance, and cardiovascular functions in miceDOI 10.1101/2023.07.24.550381Read

Transgenic mice overexpressing neuropeptide Y in noradrenergic neurons: a novel model of increased adiposity and impaired glucose tolerance.Semantic proximity Read

Firing activity of locus coeruleus noradrenergic neurons decreases in necdin-deficient mice, an animal model of Prader–Willi syndromeSemantic proximity Read

Two Specialized Intrinsic Cardiac Neuron Types Safeguard Heart Homeostasis and Stress ResilienceSemantic proximity Read

Spatial transcriptomic profiling of human paravertebral sympathetic chain ganglia reveals diabetes-induced neuroplasticitySemantic proximity Read

Tiered Sympathetic Control of Cardiac Function Revealed by Viral Tracing and Single Cell Transcriptome ProfilingSemantic proximity Read

Sympathetic innervation controls homeostasis of neuromuscular junctions in health and disease.Semantic proximity Read

Differential transcriptional profiles of vagal sensory neurons in female and male miceSemantic proximity Read

The diversity of neuronal phenotypes in rodent and human autonomic ganglia.Semantic proximity Read

Tiered sympathetic control of cardiac function revealed by viral tracing and single cell transcriptome profilingSemantic proximity Read

Activation of hypothalamic RIP-Cre neurons promotes beiging of WAT via sympathetic nervous system.Semantic proximity Read

Arcuate Nucleus of the Hypothalamus: Anatomy, Physiology, and DiseasesSemantic proximity Read

NPY and Y receptors: lessons from transgenic and knockout models.Semantic proximity Read