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Article

Hypertrophic cardiomyopathy: an up-to-date snapshot of the clinical drug development pipeline.

Expert opinion on investigational drugs - 1 Oct 2022

Tamargo Juan, Tamargo María, Caballero Ricardo

Abstract excerpt

INTRODUCTION: Hypertrophic cardiomyopathy (HCM) is a complex cardiac disease with highly variable phenotypic expression and clinical course most often caused by sarcomeric gene mutations resulting in left ventricular hypertrophy, fibrosis, hypercontractility, and diastolic dysfunction. For almost 60 years, HCM has remained an orphan disease and still lacks a disease-specific treatment. AREAS COVERED: This review...

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PMID: 36062808
DOI: 10.1080/13543784.2022.2113374

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