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Article

Genetic Contributions of Inflammation to Depression

24 Aug 2016

Abstract excerpt

This paper describes the effects of immune genes genetic variants and mRNA expression on depression's risk, severity, and response to antidepressant treatment, through a systematic review on all papers published between 2000 and 2016. Our results, based largely on case-control studies, suggest that common genetic variants and gene-expression pathways are involved in both immune activation and depression. The most...

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PMID: 27555379
DOI: 10.1038/npp.2016.169

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