Article

Dual control of host actin polymerization by a <i>Legionella</i> effector pair

2023-05-15

Abstract excerpt

<h4>ABSTRACT</h4> Host actin cytoskeleton is often targeted by pathogenic bacteria through the secretion of effectors. Legionella pneumophila virulence relies on the injection of the largest known arsenal of bacterial proteins, over 300 Dot/Icm Type 4 Secretion System effectors, into the host cytosol. Here we define the functional interactions between VipA and LegK2, two effectors with antagonistic activities to...

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Literature Corpus work: 1b416d5e-80f0-505f-97bb-d52faef08445
DOI: 10.1101/2023.05.15.540800

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