Article

Solution structure of the phosphatidylinositol 3-phosphate binding domain from the <i>Legionella</i> effector SetA

2022-02-14

Abstract excerpt

Legionella pneumophila is a facultative intracellular pathogen that causes Legionnaires’ disease or Pontiac fever in humans upon accidental inhalation of Legionella -contaminated aerosols. During infection, L. pneumophila secretes more than 300 effectors into the host for the biogenesis of a replication-permissive niche, known as the Legionella containing vacuole (LCV). Among these, a large number of effectors...

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Literature Corpus work: 82ce9d5b-1e25-5c16-b763-6d2dfc600267
DOI: 10.1101/2022.02.13.480292

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