Back to search

Article

GS-Preprocess: Containerized GUIDE-seq Data Analysis Tools with Diverse Sequencer Compatibility

2020-01-27

Abstract excerpt

RNA-guided nucleases (e.g. CRISPR-Cas) are used in a breadth of clinical and basic scientific subfields for the investigation or modification of biological processes. While these modern platforms for site-specific DNA cleavage are highly accurate, some applications (e.g. gene editing therapeutics) cannot tolerate DNA breaks at off-target sites, even at low levels. Thus, it is critically important to determine the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1b1ed6dc-ef07-5c62-be30-c2b2e125dcf4
DOI
10.1101/2020.01.26.914861
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
GS-Preprocess: Containerized GUIDE-seq Data Analysis Tools with Diverse Sequencer CompatibilityDOI 10.1101/2020.01.26.914861
SuperDecode: An integrated toolkit for analyzing mutations induced by genome editing.Semantic proximity
GREPore-seq: A Robust Workflow to Detect Changes after Gene Editing through Long-range PCR and Nanopore SequencingSemantic proximity
Massively Parallel Profiling of RNA-targeting CRISPR-Cas13dSemantic proximity
Targeted decontamination of sequencing data with CLEANSemantic proximity
CAS12A-TARGETED MULTIPLEXED NANOPORE SEQUENCINGSemantic proximity
Cas12a-Capture: a novel, low-cost, and scalable method for targeted sequencingSemantic proximity
PrimeDesign software for rapid and simplified design of prime editing guide RNAsSemantic proximity
High-throughput evaluation of in vitro CRISPR activities enables optimized large-scale multiplex enrichment of rare variants.Semantic proximity
crisprSQL: a novel database platform for CRISPR/Cas off-target cleavage assaysSemantic proximity
BATCH-GE: Batch analysis of Next-Generation Sequencing data for genome editing assessmentSemantic proximity
PrimeDesign software for rapid and simplified design of prime editing guide RNAsSemantic proximity
PrimeDesign software for rapid and simplified design of prime editing guide RNAs.Semantic proximity
Select a neighboring publication to make it the new centre.