Article

Rad51 inhibition sensitizes non-replicating quiescent cells to UVB radiation and transcription stress

2022-09-20

Abstract excerpt

DNA damage induced by environmental, occupational, and chemotherapeutic compounds lead to a variety of cellular responses that are potentially impacted by the proliferation status of the cell. Using small molecule inhibitors of various DNA doublestrand break (DSB) repair pathways in non-replicating, quiescent human cells exposed to UVB radiation, we unexpectedly observed a major role for the recombination protein...

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Literature Corpus work: 1afaa956-a31f-5802-9a27-45572db0fabe
DOI: 10.1101/2022.09.20.508657

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