Article

Targeting the DNA damage repair protein RAD51 alters fibroblast metabolism and enhances apoptosis in pulmonary fibrosis

2026-04-04

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease characterized by aberrantly activated, apoptosis-resistant profibrotic lung (myo)fibroblasts. Prior research has demonstrated that lung fibroblasts from patients with IPF exhibit resistance to DNA damage, suggesting that this behavior contributes to their persistent survival and continuous proliferati...

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Literature Corpus work: d59ed9b5-5fc6-5979-ad6e-31cc776783d8
DOI: 10.64898/2026.04.01.715935

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