Inflammation and neuronal gene expression changes differ in early versus late chronic traumatic encephalopathy brain

Abstract excerpt

BACKGROUND: Our understanding of the molecular underpinnings of chronic traumatic encephalopathy (CTE) and its associated pathology in post-mortem brain is incomplete. Factors including years of play and genetic risk variants influence the extent of tau pathology associated with disease expression, but how these factors affect gene expression, and whether those effects are consistent across the development of...

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