Article

Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones

2023-06-28

Abstract excerpt

Intratumoral cellular heterogeneity necessitates multi-targeting therapies for improved clinical benefits in patients with advanced malignancies. However, systematic identification of patient-specific treatments that selectively co-inhibit cancerous cell populations poses a combinatorial challenge, since the number of possible drug-dose combinations vastly exceeds what could be tested in scarce patient cells. Here...

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Literature Corpus work: 1a99771b-2125-5f09-8bf5-2c3e07f5e838
DOI: 10.1101/2023.06.26.546571

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