Article
The Landscape of Receptor-Mediated Precision Cancer Combination Therapy: A Single-Cell Perspective
2020-01-29
Abstract excerpt
The availability of single-cell transcriptomics data opens new opportunities for rational design of combination cancer treatments. Mining such data, we employed combinatorial optimization techniques to explore the landscape of optimal combination therapies in solid tumors including brain, head and neck, melanoma, lung, breast and colon cancers. We assume that each individual therapy can target any one of 1269 gene...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- b5c8c7c7-34a0-5ec0-a039-9215ac977514
- DOI
- 10.1101/2020.01.28.923532