Article

The Landscape of Receptor-Mediated Precision Cancer Combination Therapy: A Single-Cell Perspective

2021-10-25

Abstract excerpt

<title>Abstract</title> <p>The availability of single-cell transcriptomics data opens new opportunities for rational design of combination cancer treatments. Mining such data, we employed combinatorial optimization techniques to explore the landscape of optimal combination therapies in solid tumors including brain, head and neck, melanoma, lung, breast and colon cancers. We assume that each individual therapy can...

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Literature Corpus work: 6fc67513-b656-5e8d-872c-b9738cd99460
DOI: 10.21203/rs.3.rs-992105/v1

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