Article

Isoform and pathway-specific regulation of post-transcriptional RNA processing in human cells

2024-06-12

Abstract excerpt

<h4>ABSTRACT</h4> Steady-state levels of RNA transcripts are controlled by their rates of synthesis and degradation. Here we used nascent RNA Bru-seq and BruChase-seq to profile RNA dynamics across 16 human cell lines as part of ENCODE4 Deeply Profiled Cell Lines collection. We show that RNA turnover dynamics differ widely between transcripts of different genes and between different classes of RNA. Gene set enric...

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Literature Corpus work: 1a8f230c-2be1-5019-b269-a48da1a49950
DOI: 10.1101/2024.06.12.598705

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