Article

Antigenic stimulation in conjunction with cytokine is required for mediating IL-17A production in human MAIT cells

2026-01-30

Abstract excerpt

Mucosal-associated invariant T (MAIT) cells are donor unrestricted T cells capable of both antigen-specific adaptive responses and cytokine driven innate-like functions. Although human MAIT cells uniformly express ROR γ t and IL23R , they generally produce IFN-γ, and only a small fraction produces IL-17. Recent studies show that combined TCR and cytokine stimulation can elicit functional heterogeneity in blood-...

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Literature Corpus work: 1a778b8c-b283-50ac-b54f-fc30964283a2
DOI: 10.64898/2026.01.27.702041

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