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Article

An in vitro model of innate lymphoid cell function and differentiation.

Mucosal immunology - 1 Mar 2015

Allan D S J, Kirkham C L, Aguilar O A, Qu L C, Chen P, Fine J H, Serra P, Awong G, Gommerman J L, Zúñiga-Pflücker J C, Carlyle J R

Abstract excerpt

Innate lymphoid cells (ILC) are RAG-independent lymphocytes with important roles in innate immunity, and include group-1 (natural killer (NK) cell, ILC1), group-2 (ILC2), and group-3 (lymphoid tissue inducer (LTi), NCR(+) ILC3) subsets. Group-3 ILC express Rorγt, produce interleukin (IL)-22, and are critically important in the normal function of mucosal tissues. Here, we describe a novel model cell line for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25138665
DOI: 10.1038/mi.2014.71

Genes

CCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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