Article

Altered hypothalamic microstructure in human obesity

2019-03-29

Abstract excerpt

Obesity is a multifactorial disorder driven by sustained energy imbalance. The hypothalamus is an important regulator of energy homeostasis and therefore likely involved in obesity pathophysiology. Animal studies suggest that obesity-related diets induce structural changes in the hypothalamus through inflammation-like processes. Whether this translates to humans is however largely unknown. Therefore, we aimed to a...

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Literature Corpus work: 1a6b9568-1119-5795-abcc-dc7d2d700dec
DOI: 10.1101/593004

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