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Article

Identification of Pleiotropic Genetic Effects on Obesity and Brain Anatomy

1 Jan 2013

Abstract excerpt

BACKGROUND/AIMS: Obesity is a major contributor to the global burden of chronic disease and disability, though current knowledge of causal biologic underpinnings is lacking. Through the regulation of energy homeostasis and interactions with adiposity and gut signals, the brain is thought to play a significant role in the development of this disorder. While neuroanatomical variation has been associated with...

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PMID: 24081229
DOI: 10.1159/000353953

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