Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Body mass index, but not FTO genotype or major depressive disorder, influences brain structure.

Neuroscience - 12 Nov 2013

Cole J H, Boyle C P, Simmons A, Cohen-Woods S, Rivera M, McGuffin P, Thompson P M, Fu C H Y

Abstract excerpt

Obesity and major depressive disorder (MDD) are highly prevalent and often comorbid health conditions. Both are associated with differences in brain structure and are genetically influenced. Yet, little is known about how obesity, MDD, and known risk genotypes might interact in the brain. Subjects were 81 patients with MDD (mean age 48.6 years) and 69 matched healthy controls (mean age 51.2 years). Subjects...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Image Processing, Computer-Assisted

Share to Magnetic Resonance Imaging

Share to Obesity

Share to Oligonucleotide Array Sequence Analysis

Share to Proteins

Source

Identifiers

PMID: 23933215
DOI: 10.1016/j.neuroscience.2013.07.015

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Body mass index, but not FTO genotype or major depressive disorder, influences brain structure.PMID 23933215Read ↗

The obese brain as a heritable phenotype: a combined morphometry and twin study.Semantic proximity Read ↗

Depressive disorder moderates the effect of the FTO gene on body mass index.Semantic proximity Read ↗

Relationship between a BDNF gene polymorphism and the brain volume in treatment-naive patients with major depressive disorder: A VBM analysis of brain MRI.Semantic proximity Read ↗

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly.Semantic proximity Read ↗

Prefrontal gray matter volume mediates genetic risks for obesity.Semantic proximity Read ↗

Two human brain systems micro-structurally associated with obesitySemantic proximity Read ↗

From the reward network to whole-brain metrics: structural connectivity in adolescents and young adults according to body mass index and genetic risk of obesity.Semantic proximity Read ↗

Shared Genetic Underpinnings of Gray Matter Volume Alterations and Metabolic Traits in Major Depressive DisorderSemantic proximity Read ↗

Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study.Semantic proximity Read ↗

Causal Association Between Major Depressive Disorder and Cortical Structure: A Bidirectional Mendelian Randomization Study and Mediation Analysis.Semantic proximity Read ↗

Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder.Semantic proximity Read ↗

Association of the fat mass and obesity-associated gene risk allele, rs9939609A, and reward-related brain structures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.