Article

The atypical antipsychotic aripiprazole alters the outcome of disseminated <i>Candida albicans</i> infections

2024-02-14

Abstract excerpt

Invasive fungal infections (IFIs) impose an enormous clinical, social, and economic burden on humankind. For many IFIs, ≥ 30% of patients fail therapy with existing antifungal drugs, including the widely used azole class. We previously identified a collection of 13 approved medications that antagonize azole activity. While gain-of-function mutants resulting in antifungal resistance are often associated with reduce...

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Literature Corpus work: 46139dd1-c615-5dad-b5fe-a8cb6ed0c4ae
DOI: 10.1101/2024.02.13.580133

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