Article

Depletion of aneuploid cells is shaped by cell-to-cell interactions

2024-12-16

Abstract excerpt

<h4>Summary</h4> Aneuploidy, the major cause of miscarriages in humans, is pervasive in early embryos but robustly dampened during development, allowing for healthy births. Later in life, aneuploidy correlates with pathological conditions including cancer. Identification of the mechanisms underlying the elimination of aneuploid cells is relevant in development and disease. Here we generated cells carrying molecul...

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Literature Corpus work: 1a41339c-711c-5083-8ad9-cf8335929f9b
DOI: 10.1101/2024.12.11.627746

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